Advanced Liposomal Delivery MSM (methylsulfonylmethane) is a naturally occurring form of organic sulfur. MSM Cream can be used to soften and smooth skin while adding oil-rich, moisture-binding protection. Liposome technology is an exceptional method for topical penetration and absorption of key ingredients. Liposomes are tiny spheres which easily penetrate the skin to deliver the MSM Cream. MSM Cream also contains the potent antioxidants vitamin E and ginkgo. Source Naturals also makes MSM tablets for internal use.